egnite Research

Advancing cardiovascular research through egnite’s real-world evidence.

Contemporary Practice Patterns and Outcomes for Patients With Mitral Regurgitation: Results From a Large Multicenter Real-World Database

“These findings underscore the urgency of early intervention for patients with MR. The implications of delayed treatment, particularly in moderate-to-severe MR, cannot be overstated, as it may lead to poor patient outcomes.” Rahul Sharma, MBBS, FRACPDirector of Structural Interventions, Stanford Healthcare, Associate Director of the Cardiac Catheterization Laboratory and Clinical

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The Mortality Burden of Untreated Aortic Stenosis

“This research is the first of its kind to look at such a large cohort of AS patients over a four-year span. Findings serve as a stark reminder of the poor prognosis associated with untreated AS irrespective of severity, suggesting patients with moderate AS may benefit from intervention.” Philippe Généreux,

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Prognostic Impact of Cardiac Damage Across the Spectrum of Aortic Stenosis Severity: Results From a Large Real-World Database

“These results further underscore the poor prognosis associated with untreated aortic stenosis of any severity and provide meaningful insights for the management of this patient population.”Philippe Généreux, MD, FACC Director of the Structural Heart Program of Morristown’s Gagnon Cardiovascular Institute and lead author of the study. BACKGROUND Previously, we described

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Outcomes With Guideline-Directed Medical Therapy and Cardiac Implantable Electronic Device Therapies For Patients With Heart Failure With Reduced Ejection Fraction

“Over the last five years, new therapies to treat heart failure emerged with promising improvements in survival benefit. This study represents the first time we’ve seen an assessment of ‘5-class’ guideline-directed therapy — up to 4 foundational medication classes plus ICD/CRT-D therapy — for these patients. The next big challenge

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