egnite Research

Advancing cardiovascular research through egnite’s real-world evidence.

Outcomes With Guideline-Directed Medical Therapy and Cardiac Implantable Electronic Device Therapies For Patients With Heart Failure With Reduced Ejection Fraction

“Over the last five years, new therapies to treat heart failure emerged with promising improvements in survival benefit. This study represents the first time we’ve seen an assessment of ‘5-class’ guideline-directed therapy — up to 4 foundational medication classes plus ICD/CRT-D therapy — for these patients. The next big challenge

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Artificial Intelligence-Enabled Predictive Model of Progression From Moderate to Severe Aortic Stenosis

BACKGROUND Progression from moderate to severe aortic stenosis (AS) warrants careful monitoring due to the increased risk of sudden death and heart failure, with disease progression significantly varying among patients and no accurate predictive tools presently available. OBJECTIVE A Disease Progression Algorithm was developed from a deidentified database of 1,163,923

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