
The Mortality Burden of Untreated Aortic Stenosis
“This research is the first of its kind to look at such a large cohort of AS patients over a four-year span. Findings serve as a stark reminder of the poor prognosis associated with untreated AS irrespective of severity, suggesting patients with moderate AS may benefit from intervention.” Philippe Généreux,
Prognostic Impact of Cardiac Damage Across the Spectrum of Aortic Stenosis Severity: Results From a Large Real-World Database
“These results further underscore the poor prognosis associated with untreated aortic stenosis of any severity and provide meaningful insights for the management of this patient population.”Philippe Généreux, MD, FACC Director of the Structural Heart Program of Morristown’s Gagnon Cardiovascular Institute and lead author of the study. BACKGROUND Previously, we described

Gaps in Contemporary Echocardiographic Reporting Quality for Mechanisms of Mitral Regurgitation: A Call to Action
Mitral regurgitation (MR) is highly prevalent both in the United States and worldwide and is an important determinant of morbidity and mortality.[1] The mechanisms of MR are divided broadly into primary (affecting valve leaflets) and secondary (affecting nonvalvular structures such as the left ventricle or atrium).2 Mixed MR occurs when

Clinical Journey for Patients with Aortic Regurgitation: A Retrospective Observational Study From a Multicenter Database
“This is one of the first artificial intelligence-driven studies providing critical insights into care patterns for patients with moderate or greater AR in the community. The urgency for digital technologies to identify AR patients earlier and novel therapies to improve outcomes for this vulnerable patient population has never been greater.”

Outcomes With Guideline-Directed Medical Therapy and Cardiac Implantable Electronic Device Therapies For Patients With Heart Failure With Reduced Ejection Fraction
“Over the last five years, new therapies to treat heart failure emerged with promising improvements in survival benefit. This study represents the first time we’ve seen an assessment of ‘5-class’ guideline-directed therapy — up to 4 foundational medication classes plus ICD/CRT-D therapy — for these patients. The next big challenge
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